Dog ate chocolate?

ask a vet

Side effects of Trilostane.

Species: Dog
Breed: Boston Terrier
Age: 8-11 years
Buddy was diagnosed with Cushings Disease about 5 weeks ago. He had extensive blood work done and an ultrasound to verify that he has enlarged adrenal glands. We were given Trilostane (15 mg. twice a day) for 2 weeks. AFter 2 weeks he had blood work done once again and our vet said we should increase to 20 mg twice a day for another 2 or 3 weeks. We are at the 2 week point. Buddy is definitely not urinating as often and his drinking has slowed down, but he is shaking all the time - front and back legs. He walks around the house, stops and just stares off with his ears back, shaking. It breaks our hearts to see him this way. We are assuming the shaking is pain, but could it also be another symptom of the Cushings progressing? We have another appointment with our vet tomorrow and of course we will be asking all these questions, but we just are not seeing quality of life right now and just don't know what to do. Any thoughts from you will be greatly appreciated.


Online vet, Dr. Marie

Dr. Marie replied:

I feel for you! Cushing's is a difficult disease to treat. The good news is that once you and your vet get the dosage of Trilostane levelled out then it is usually quite simple from that point on.

I am actually quite concerned by what you have described with Buddy and I think that you will need to see your vet today rather than tomorrow. It's possible that he has become Addisonian. I'll see if I can explain:

What the Trilostane does is block adrenal hormone from being produced and used by the body. (When Buddy was first diagnosed, he had way too much adrenal hormone and this is what caused the Cushing's symptoms.) However, it's possible to block too much of this hormone.

If a dog does not get enough adrenal hormone then they can get something called Addison's disease. Addison's is very serious and life threatening.

The symptoms of shaking, reduction of appetite and thirst and lethargy can be a sign of Addison's.

Your vet will likely want to do some blood tests today. If they feel that Buddy is Addisonian then they will give him some steroids. There will be an adjustment period where they figure out when he can go back on Trilostane and what dose he should be taking for the long term.

It is of course possible that there is something else going on. But what you are describing does not sound normal and definitely sounds worthy of an immediate vet visit.

I hope he does ok!

Dr. Marie.



Check out our dog age calculator and cat age calculator.

Want to receive pet coupons, vet advice and info on new pet products in your inbox?

* indicates required

We'll only send you great stuff, never spam. Unsubscribe any time.

Disclaimer: Although Dr. Marie is a qualified veterinarian, the information found on this site is not meant to replace the advice of your own veterinarian. AskAVetQuestion.com and Dr. Marie do not accept any responsibility for any loss, damage, injury, death, or disease which may arise from reliance on information contained on this site. Do not use information found on this site for diagnosing or treating your pet. Anything you read here is for information only.

Customer reply:

THank you so much for your quick response!! I have a call in to my vet requesting that Buddy be seen today. Thank you for the information about Addison's - we are not familiar with that. All we want is for Buddy to be as well as he can be and have quality of life. Thanks again.
Shari


Search for similar questions:

ask a vet

Popular questions...

Cancer or hairball? Mama Kitty has a lower abdomen mass. She is 5 lbs. The vet suspects cancer, although... (10558 views)

Dogs with occasional diarrhea. I have two German shepherds, male and female. The female is 7 yrs, the male is 5... (20656 views)

Sore leg in 16 year old cat. Hello We have a cat that is about 16 years old. The last couple of days she has... (3277 views)

Bloated abdomen my dog has been severly bloated for five weeks, at first i thought he had just got... (9428 views)

Surgery or rest for CCL tear. Dear Dr. Marie, My dog often limping recently and i've brought her to see a vet in... (6806 views)

Swollen feet. hey doctor, i have a weimarner....for the last 1 year he has been continuously... (4925 views)

Rat bleeding from eye. It started about 4-5 weeks ago when I noticed my girl was bleeding from her eye and... (13163 views)

Lump on Rottweiler's leg. Dear Dr Marie Recently, I notice my dog has a lump or growth(white round bumpy... (10423 views)

Peeing outside of box. Hi Dr Marie, My Cat Nikki is 21 yrs old......he was shot in the mouth when he was... (6314 views)

Female dog humping. My female pit bull everyday, anytime I lay down on my couch or bed, she jumps up on... (6270 views)

See all questions...

Dr. MarieDr. Marie is a veterinarian who practices in a busy animal hospital in Ottawa, Ontario. She created Ask A Vet Question as a resource for good, accurate veterinary advice online. Dr. Marie treats dogs, cats, hamsters, guinea pigs, and rats. She has been a vet since 1999.

Is an online vet visit just as good as a trip to your veterinarian? No! But, many times, asking an online veterinarian a question can help save you money. While Dr. Marie can't officially diagnose your pet or prescribe medications, she can often advise you on whether a vet visit is necessary. You can also ask Dr. Marie for a second opinion on your pet's condition.