Dog ate chocolate?

ask a vet

Phenobarbital and Zonisamide.

Species: Dog
Breed: miniature poodle
Age: 5-8 years
Ziggy had cluster seizures as a puppy and we have been controlling them (averages 1/month) with a combination of Phenobarbital and Potassium Bromide. His latest Bile Acid level was 45.1, up from 27.6 six months ago. His ALP and GGT levels have always been high according to my vet because of the phen barb.
He has recommended we transition him off the phen barb and on to 100 mg Zonisamide taking them both as we taper off the phen barb slowly.
Does this sound like a good idea to you or should we have further tests done to verify the most recent Bile Acid test and/or liver damage? He has a bad tooth to deal with at the same time. Can a decaying tooth effect the Bile Acid level?
We are planning on taking care of the tooth first then dealing with the medication transition. The last time he had a tooth removed he had his worst seizure to date.
Would love your opinion on this. Thank you.


Online vet, Dr. Marie

Dr. Marie replied:

I'm sorry to hear about Ziggy's recent problems. Seizures can be very frustrating to deal with. A bile acid level of 45.1 does indeed sound high. High bile acids can often be a sign that the liver function is impaired, and as we know that phenobarbital can be hard on the liver, it's not wise to stay on it if there is risk of liver damage. There is certainly no harm in asking your vet to repeat the bile acids test as occasionally we can get misleading results.

But, it does sound like your vet is doing the same things that I would do.

It's unlikely that a dental issue would affect the bile acids, so I wouldn't think that this is the problem.

If you do transition the medications (which sounds like the wise things to do) I hope things go well.

Dr. Marie.


Do you have a pet website? Interested in learning more about SEO for Wix?


Check out our dog age calculator and cat age calculator.

Want to receive pet coupons, vet advice and info on new pet products in your inbox?

* indicates required

We'll only send you great stuff, never spam. Unsubscribe any time.

Disclaimer: Although Dr. Marie is a qualified veterinarian, the information found on this site is not meant to replace the advice of your own veterinarian. AskAVetQuestion.com and Dr. Marie do not accept any responsibility for any loss, damage, injury, death, or disease which may arise from reliance on information contained on this site. Do not use information found on this site for diagnosing or treating your pet. Anything you read here is for information only.

Search for similar questions:

ask a vet

Popular questions...

Nursing cat has no milk. she has difficulty producing milk; one time losing milk early, the second she... (10725 views)

Not eating, losing weight. My cat has lost a lot of weight in the past 3 weeks. She cries for food but then... (9333 views)

Pseudomonas aeruginosa in cats. My cat is aged 9. She was recently diagnosed with Pseudomonas aeruginosa which is... (33202 views)

Renal lymphoma? my cat just had dental surgery. After about a week I noticed she was still listless... (25374 views)

Pocket pets and cats. I have been considering adding a small pocket pet as a companion to my home. I... (3586 views)

arthritis in 17 year old dog I have a 17 year old female german shepard/black lab/collie mix that weighs 45... (80473 views)

Dark spot on eye. scooby recently has a darker spot on his pupil, other than that his health is... (27593 views)

Can't pee. Constipation issues too. Hello, My cat has Mega Colon and is being treated with CisaPride 5mg/ml suspension.... (12768 views)

Shedding Akita. my akita is 14 months old and is lossing massive clumps of fur. he has new curse... (8934 views)

Diarrhea and increased appetite. We found a cat that we have decided to keep. We have had all his shots, Neutered and... (5099 views)

See all questions...

Dr. MarieDr. Marie is a veterinarian who practices in a busy animal hospital in Ottawa, Ontario. She created Ask A Vet Question as a resource for good, accurate veterinary advice online. Dr. Marie treats dogs, cats, hamsters, guinea pigs, and rats. She has been a vet since 1999.

Is an online vet visit just as good as a trip to your veterinarian? No! But, many times, asking an online veterinarian a question can help save you money. While Dr. Marie can't officially diagnose your pet or prescribe medications, she can often advise you on whether a vet visit is necessary. You can also ask Dr. Marie for a second opinion on your pet's condition.