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Cerenia and buprenorphine

Species: Cat
Breed: dsh
Age: More than 15 ye
My 18 year old cat was given a shot of cerenia and then 12 hours later I gave her .06 ml of buprenorphine.Will the two meds together cause her to be oversedated?
She weights 4.4 pounds

Can she pass out because of these two meds and can respiratory arrest occur at her age as I have read online.
Is there a proper way ti handle sedated cats while on these meds.


Online vet, Dr. Marie

Dr. Marie replied:

Hi and thanks for your question. These are questions that really do need to be answered by the vet who prescribed these medications for your cat. I can give you some general ideas of what to expect though.

I was not able to find any case reports of cats who had problems when given cerenia and buprenorphine at the same time. Cerenia is generally well tolerated by cats and should not cause respiratory suppression. The drug label for this medication does not indicate any known drug interactions.

Buprenorphine can cause some sedation in cats. While there are many drugs that can interact with buprenorphine or cause the side effects to be exaggerated, cerenia is not on the list.

In my opinion these drugs are probably safe to use together provided that both were prescribed by your veterinarian. If, however, you are worried or if your cat does seem overly sedated then there may be another issue going on and going back to the vet would be an excellent idea.

I hope this helps to clear things up.

Dr. Marie



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Disclaimer: Although Dr. Marie is a qualified veterinarian, the information found on this site is not meant to replace the advice of your own veterinarian. AskAVetQuestion.com and Dr. Marie do not accept any responsibility for any loss, damage, injury, death, or disease which may arise from reliance on information contained on this site. Do not use information found on this site for diagnosing or treating your pet. Anything you read here is for information only.

Customer reply:

Thanks for your answer.
I guess because I read that buprenorphine can cause respiratory depression,if it were to happen that my cat would stop breathing while at home what is the best way to respond.
Should I lye her in a certain position abd is cpr successful on an elderly cat?


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Dr. MarieDr. Marie is a veterinarian who practices in a busy animal hospital in Ottawa, Ontario. She created Ask A Vet Question as a resource for good, accurate veterinary advice online. Dr. Marie treats dogs, cats, hamsters, guinea pigs, and rats. She has been a vet since 1999.

Is an online vet visit just as good as a trip to your veterinarian? No! But, many times, asking an online veterinarian a question can help save you money. While Dr. Marie can't officially diagnose your pet or prescribe medications, she can often advise you on whether a vet visit is necessary. You can also ask Dr. Marie for a second opinion on your pet's condition.