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Ketoconazole, Heartgard, Comfortis.

Species: Dog
Breed: Papillon
Age: 5-8 years
Good morning. Well this is kind of a follow-up question on Poppi. I wrote to you on the safety of the antu-fungal Ketoconazole, and your answer was spot-on. He's doing very well and seems back to his old self although he still has 2 more weeks of treatments (and prescription baths every 3 days) to go.
My new question is, its time for my dogs monthly Comfortis / Heartguard treatment, and I want to make sure its safe to give him these while on his other medicine. He's such a little dog and I dont want to overload his system.
Thanks again, Have a great weekend,
Tina


Online vet, Dr. Marie

Dr. Marie replied:

I'm glad to hear that Poppi is improving. Yay!

Your question about Poppi's heartworm and flea medication is actually one that you will need to ask your vet about as I can't legally advise on medication online.

Ketoconazole is not supposed to be used with Ivermectin as it can increase the chances of Ivermectin toxicity. Heartgard contains ivermectin. However, it contains a very tiny dosage of it and I think that the chances of developing a toxicty would be extremely small.

The general consensus among vets is that this risk is only a problem for dogs who are on daily doses of ivermectin such as for treatment of demodectic mange. A single monthly minisucle dose such as what we see in Heartgard is very unlikely to cause a problem.

Ketoconazole should be safe with spinosad, the ingredient in Comfortis.

I think you should be fine, but I would highly suggest that you get your vet's opinion in Poppi's case.

Dr. Marie.


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Disclaimer: Although Dr. Marie is a qualified veterinarian, the information found on this site is not meant to replace the advice of your own veterinarian. AskAVetQuestion.com and Dr. Marie do not accept any responsibility for any loss, damage, injury, death, or disease which may arise from reliance on information contained on this site. Do not use information found on this site for diagnosing or treating your pet. Anything you read here is for information only.

Customer reply:

Thanks Dr. Marie, I'll do that.
Now I's so glad I asked instead of giving it to him.

Sincerely, Tina


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Dr. MarieDr. Marie is a veterinarian who practices in a busy animal hospital in Ottawa, Ontario. She created Ask A Vet Question as a resource for good, accurate veterinary advice online. Dr. Marie treats dogs, cats, hamsters, guinea pigs, and rats. She has been a vet since 1999.

Is an online vet visit just as good as a trip to your veterinarian? No! But, many times, asking an online veterinarian a question can help save you money. While Dr. Marie can't officially diagnose your pet or prescribe medications, she can often advise you on whether a vet visit is necessary. You can also ask Dr. Marie for a second opinion on your pet's condition.