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Does Prozac cause diarrhea in dogs?

Species: Dog
Breed: dog
Age: 2-5 years
I want to know if continuing diarrhea is a possible side effect of prozac. My dog weighs about
65 to 70 pounds and has been on 20 mg of fluoxetine for about two months. Not too long after
I started giving her the pill, she started with the diarrhea. I put her on the rice and cottage cheese
diet and once daily add 1 packet of FortiFlora, but there is no change. Should I remove the prozac
and see if the diarrhea clears up, or are the two unrelated?


Online vet, Dr. Marie

Dr. Marie replied:

Thanks for your question.

The following side effects are listed for Prozac when used for dogs:

  • lethargy

  • Gastrointestinal effects

  • anxiety

  • irritability

  • insomnia

  • panting



As gastrointestinal effects are listed as a side effect then yes, diarrhea could be caused by the Prozac.

Unfortunately we don't have a lot of research on using Prozac in dogs so we often don't have clear guidelines as to what to expect.

I would not recommend stopping the Prozac without instructions from your vet as dogs, just like people, can have side effects from stopping Prozac too quickly.

It is also possible that there is something else causing the diarrhea. Unfortunately it can often be hard to know what the cause is.

If this were my case I would likely be trying a gradual change to another anti-anxiety medication such as Clomicalm (but this depends on why your dog was put on Prozac). I might also try a course of metronidazole which is an antibiotic which can help with intestinal inflammation. I would likely also be suggesting a fecal check for parasites as well.

I hope things are ok soon!

Dr. Marie.


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Disclaimer: Although Dr. Marie is a qualified veterinarian, the information found on this site is not meant to replace the advice of your own veterinarian. AskAVetQuestion.com and Dr. Marie do not accept any responsibility for any loss, damage, injury, death, or disease which may arise from reliance on information contained on this site. Do not use information found on this site for diagnosing or treating your pet. Anything you read here is for information only.

Customer reply:

Thank you for your reply. Deja was put on prozac when I trainer I contracted with stated she showed many symptoms of anxiety, growling when approached or at new people, suckling a favorite blanket and teeth baring to make her point. He said he didn't want to start training until the prozac was tried for six weeks. I will contact the vet who prescribed the prozac and mention the alternative. Thank you again.
S. D'Spain


Online vet, Dr. Marie

Dr. Marie replied:

You're very welcome. I hope Deja is feeling better soon!

Dr. Marie



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Dr. MarieDr. Marie is a veterinarian who practices in a busy animal hospital in Ottawa, Ontario. She created Ask A Vet Question as a resource for good, accurate veterinary advice online. Dr. Marie treats dogs, cats, hamsters, guinea pigs, and rats. She has been a vet since 1999.

Is an online vet visit just as good as a trip to your veterinarian? No! But, many times, asking an online veterinarian a question can help save you money. While Dr. Marie can't officially diagnose your pet or prescribe medications, she can often advise you on whether a vet visit is necessary. You can also ask Dr. Marie for a second opinion on your pet's condition.